Here are two early signs that can sometimes point to pancreatic cancer, an often-fatal cancer because it’s usually diagnosed late. These signs are nonspecific, so having them doesn’t mean someone has pancreatic cancer—but they should prompt medical evaluation.
1. Unexplained Weight Loss (often with loss of appetite)
People may begin losing weight without trying. This can happen because:
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The pancreas isn’t producing enough digestive enzymes
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Food isn’t being properly absorbed
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Tumors may reduce appetite or change metabolism
Weight loss is one of the most common early clinical clues.
2. Jaundice (Yellowing of Skin or Eyes)
A tumor in the head of the pancreas can block the bile duct, causing:
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Yellowing of the skin or eyes
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Dark urine
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Light-colored stools
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Itchy skin
Jaundice is sometimes one of the first visible signs that brings a patient to the doctor.
Other Early or Common Symptoms (Not part of the “two,” but important)
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Upper abdominal or back pain
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New-onset diabetes, especially in adults without risk factors
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Digestive problems (bloating, nausea, greasy stools)